High-Speed Label-Free Spectroscopic Biological Imaging Based on Stimulated Raman Scattering MicroscopyHigh-Speed Label-Free Spectroscopic Biological Imaging Based on Stimulated Raman Scattering MicroscopyHigh-Speed Label-Free Spectroscopic Biological Imaging Based on Stimulated Raman Scattering Microscopy
نویسندگان
چکیده
منابع مشابه
Label-Free Biomedical Imaging Using High-Speed Lock-In Pixel Sensor for Stimulated Raman Scattering
Raman imaging eliminates the need for staining procedures, providing label-free imaging to study biological samples. Recent developments in stimulated Raman scattering (SRS) have achieved fast acquisition speed and hyperspectral imaging. However, there has been a problem of lack of detectors suitable for MHz modulation rate parallel detection, detecting multiple small SRS signals while eliminat...
متن کاملLabel-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy.
Label-free chemical contrast is highly desirable in biomedical imaging. Spontaneous Raman microscopy provides specific vibrational signatures of chemical bonds, but is often hindered by low sensitivity. Here we report a three-dimensional multiphoton vibrational imaging technique based on stimulated Raman scattering (SRS). The sensitivity of SRS imaging is significantly greater than that of spon...
متن کاملLabel-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopy.
The recently developed Coherent Anti-stokes Raman Scattering (CARS) microscopy and Stimulated Raman Scattering (SRS) microscopy have provided new methods to visualize the localization and regulation of biological molecules without the use of invasive and potentially perturbative labels. They allow rapid imaging of specific molecules with high resolution and sensitivity. These tools have been ef...
متن کاملLabel-free DNA imaging in vivo with stimulated Raman scattering microscopy
MEDICAL SCIENCES, APPLIED PHYSICAL SCIENCES Correction for “Label-free DNA imaging in vivo with stimulated Raman scattering microscopy,” by Fa-Ke Lu, Srinjan Basu, Vivien Igras, Mai P. Hoang, Minbiao Ji, Dan Fu, Gary R. Holtom, Victor A. Neel, Christian W. Freudiger, David E. Fisher, and X. Sunney Xie, which appeared in issue 37, September 15, 2015, of Proc Natl Acad Sci USA (112:11624–11629; f...
متن کاملIn situ label-free imaging of hemicellulose in plant cell walls using stimulated Raman scattering microscopy
BACKGROUND Plant hemicellulose (largely xylan) is an excellent feedstock for renewable energy production and second only to cellulose in abundance. Beyond a source of fermentable sugars, xylan constitutes a critical polymer in the plant cell wall, where its precise role in wall assembly, maturation, and deconstruction remains primarily hypothetical. Effective detection of xylan, particularly by...
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ژورنال
عنوان ژورنال: The Review of Laser Engineering
سال: 2017
ISSN: 0387-0200,1349-6603
DOI: 10.2184/lsj.45.6_328